Toxicology Approaches in Drug Discovery

The field of toxicology has changed significantly over the last decade, toxicology experts are stepping away from traditional techniques and are shifting towards novel methods for assessing toxicity. More specifically, they are embracing the advancing areas of cell culture, molecular biology and use of computer modelling for toxicological outcome prediction.

Toxicology is the scientific study of adverse effects that occur in living organisms due to chemicals. It involves observing and reporting symptoms, mechanisms, detection and treatments of toxic substances, in particular relation to the poisoning of humans.

It includes environmental agents and chemical compounds found in nature, as well as pharmaceutical compounds that are synthesized for medical use by humans. These substances may produce toxic effects in living organisms including disturbance in growth patterns, discomfort, disease and death.